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For prescriptions the place a measuring product will not be furnished, a pharmacist can offer an ideal calibrated measuring product and can offer Guidelines for measuring the correct dose.
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Excessively huge dosages of antihistamines, such as promethazine hydrochloride, in pediatric sufferers may cause unexpected Demise (see OVERDOSAGE). Hallucinations and convulsions have transpired with therapeutic doses and overdoses of promethazine hydrochloride in pediatric clients. In pediatric people who're acutely unwell connected with dehydration, There is certainly an increased susceptibility to dystonias with the use of promethazine HCl.
Promethazine should be made use of with warning in clients with bone marrow despair. Leukopenia and agranulocytosis are actually noted, commonly when promethazine HCl has long been used in Affiliation with other regarded marrow-toxic agents.
This solution may have inactive elements, which can lead to allergic reactions or other complications. Check with your pharmacist For additional aspects.
Due to the hazards of addiction, abuse, and misuse with opioids, even at advised doses [see Warnings and Precautions (five.1)], reserve Promethazine HCl and Codeine Phosphate Oral Remedy for use in adult clients for whom the advantages of cough suppression are expected to outweigh the threats, and in whom an adequate evaluation on the etiology of the cough has long been manufactured.
The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric people less than 6 yrs of Promethazine codeine syrup age, due to the fact the combination may result in deadly respiratory depression in this age population (see WARNINGS – Box Warning and Use In Pediatric Individuals).
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Promethazine HCl and Codeine Phosphate Oral Remedy exposes people as well as other consumers to the challenges of opioid addiction, abuse, and misuse, which can result in overdose and death. Reserve Promethazine HCl and Codeine Phosphate Oral Solution to be used in adult individuals for whom the key benefits of cough suppression are anticipated to outweigh the pitfalls, As well as in whom an suitable evaluation on the etiology on the cough is produced.
Propulsive peristaltic waves while in the colon are diminished, when tone can be elevated to the point of spasm resulting in constipation. Other opioid-induced consequences could involve a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.
Throughout pregnancy, this medication need to be utilized provided that Plainly desired. Talk about the dangers and Rewards with all your doctor.
Codeine is known being significantly excreted with the kidney, and the potential risk of adverse reactions to this drug could be bigger in people with impaired renal perform.
Dosing The dose of this medication are going to be distinctive for various people. Follow your medical doctor's orders or even the directions around the label. The subsequent info features only the typical doses of this medicine. If the dose is different, don't alter it Except if your doctor tells you to do so.